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Beseha
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The 30-second answer
No study we opened compares taking probiotics before or after food, so follow the dose and timing printed on the pack. On weight: a review of 26 trials (1,720 people with overweight) found a slight fall in weight (0.70 kg) with probiotics, so there is no evidence it adds weight, though it is not a slimming product either. The common side effects are mild bloating or gas, and if you have weak immunity, are pregnant or have pancreatitis, ask a doctor first.
What is the difference between the two products?
#1
10 billion CFUSingle strain
Bacillomisk Advanced Probiotic – 20 Capsules
Lactobacillus reuteri for gut flora balance and digestive comfort
EGP 195
20 capsules · current price from the product page
- The page: 10 billion CFU of Lactobacillus reuteri per capsule
- The page: 20 capsules, and the company on the pack is Dawaa Pharma
- The page: a food supplement, not a drug
Heads-up: The page says one capsule a day in one place and two a day in the bundle maths: follow what is printed on the pack
#2
10 billion CFUProbiotic + enzymes
RotaDigest Probiotic – 30 Capsules
Two bacteria with inulin and five digestive enzymes
EGP 390
30 capsules · current price from the product page
- The page: 5 billion Bacillus coagulans and 5 billion Bacillus subtilis (10 billion in total)
- The page: inulin 134 mg and the enzymes amylase, protease, lactase, lipase and cellulase
- The page: 30 capsules and a serving of one capsule
Heads-up: The page does not state how many times a day: follow the dose printed on the pack or your doctor or pharmacist’s advice
| Bacillomisk | RotaDigest | |
|---|---|---|
| Bacteria | Lactobacillus reuteri (single strain) | Bacillus coagulans and Bacillus subtilis |
| Total units | 10 billion CFU | 10 billion CFU |
| Extras | None | Inulin 134 mg and 5 digestive enzymes |
| Pack | 20 capsules | 30 capsules |
| Cautions on the page | Pregnancy, breastfeeding, severe immune deficiency, a chronic condition and medicines needing supervision | Weak immunity, pancreatitis and digestive tract injury; ask about timing with antibiotics |
Before or after food?
The Bacillomisk page says to take the printed dose with a glass of water, preferably at the same time each day. The RotaDigest page says to take the capsule with enough water and follow the pack. Neither page specifies “before” or “after” food. We did not open a study comparing the two timings: in the 2021 Wauters trial (on Bacillus coagulans and Bacillus subtilis) the dose was twice daily for 8 weeks, and the abstract gives no link to meals. The honest answer: follow what is printed on the pack, and most importantly keep to the same time each day. If you feel discomfort, ask the pharmacist.
Possible side effects
The RotaDigest page says some people may notice bloating, gas or mild digestive discomfort. In the 2021 Wauters trial (68 patients with dyspepsia, 8 weeks) adverse events were 16% with the Bacillus probiotic versus 33% with placebo, but the trial is small and exploratory and its strains (MY01 and MY02) are not necessarily the product’s strains. For caution: weak immunity, pregnancy, breastfeeding, pancreatitis and medicines needing medical supervision, as both product pages say.
Does it add weight?
The 2021 Pontes review (26 trials, 1,720 people with overweight or obesity) found probiotics lowered weight by about 0.70 kg, BMI by 0.24, waist circumference by 1.13 cm and fat mass by 0.71 kg, with the fat loss appearing at a dose of 10 billion units or more for 8 weeks or more. The 2026 Liu review (12 trials) found a 0.52 kg fall in weight. The difference is small and the studies are in people with overweight and with different strains, so this means there is no evidence probiotics add weight, not that it is a slimming product.
With antibiotics
The 2012 Hempel review in JAMA (63 trials, 11,811 people) found probiotics were linked to less antibiotic-associated diarrhoea (risk ratio 0.58, 0.50 to 0.68), but the authors said the evidence is not enough to say which preparation or strain is better. The Bacillomisk page says to leave a gap between the antibiotic and the probiotic, and the RotaDigest page says to ask your doctor or pharmacist about timing.
Ask a doctor or pharmacist first if
- Your immunity is weak or you take immunosuppressant medicines.
- You are pregnant or breastfeeding.
- You have pancreatitis or a digestive tract injury.
- You take an antibiotic or regular medicines and want to know the timing.
- Digestive symptoms are chronic or come with blood in the stool or unexplained weight loss: that needs a doctor, not a supplement.
Want to ask?
Beseha pharmacists answer on WhatsApp. Tap the “Ask a pharmacist” button and tell them your medicines before you start.
FAQ
Bacillomisk before or after food?
The product page does not specify; it says to take the printed dose with a glass of water at the same time each day. We opened no study comparing the timings, so follow the pack.
RotaDigest before or after food?
The page does not specify and says to follow the pack. The serving is one capsule, and the number of times a day is not stated on the page.
Do probiotics add weight?
A review of 26 trials found a slight fall in weight (0.70 kg) in people with overweight, so there is no evidence they add weight, and they are not a slimming product.
Do they have side effects?
Bloating, gas or mild discomfort according to the RotaDigest page; ask a doctor if your immunity is weak, you are pregnant or have pancreatitis.
Can I take it with an antibiotic?
The 2012 JAMA review found less antibiotic-associated diarrhoea (risk ratio 0.58). The Bacillomisk page says to leave a gap between the two, and ask the pharmacist about timing.
Which of the two is better?
There is no head-to-head comparison; Bacillomisk is a single strain (L. reuteri), and RotaDigest is Bacillus bacteria with inulin and enzymes. Choose by your aim and ask the pharmacist.
Read next: best probiotics in Egypt and gut health in numbers.
The bottom line
There is no opened evidence on timing before or after food, so follow the pack and fix a time. There is no evidence probiotics add weight, and the side effects are usually mild (gas and bloating), but if your immunity is weak, you are pregnant or you take an antibiotic, ask before you start. The two products differ in strain and extras, so choose by your aim.
Bacillomisk at Beseha → RotaDigest at Beseha →
Sources
- Pontes et al. 2021: probiotics and body adiposity in overweight and obesity, meta-analysis
- Liu et al. 2026: probiotics for body weight management, meta-analysis of 12 trials
- Hempel et al. 2012 (JAMA): probiotics and antibiotic-associated diarrhoea
- Wauters et al. 2021: spore-forming probiotics in functional dyspepsia, pilot trial
- Bacillomisk product page at Beseha
- RotaDigest Probiotic product page at Beseha
This content is for information and is not a substitute for advice from a doctor or pharmacist. Prices and availability may change; the final price is on the product page.
