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ImmuGuard: Side Effects and Who Should Ask a Doctor First

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ImmuGuard: side effects and who should ask a doctor first

Reviewed by the Beseha pharmacist team · Updated 13 November 2026 · The numbers come from published PubMed studies, the product page and the box · 7-minute read

The 30-second answer

ImmuGuard is a food supplement registered with the Egyptian National Food Safety Authority (2022/3652) and contains bovine colostrum and skimmed milk, so it is not for anyone with a cow’s milk protein allergy. In the Assiut study of 160 children, mild effects (rash, itch and diarrhoea) appeared in 12 children, which is 7.5 percent, and in the 2026 Ain Shams study of 60 children no adverse events were recorded. Both studies are small and short, so ask the child’s doctor first, especially if the child is under 6 months or has an allergy or a chronic condition, and it is not a substitute for rehydration solution.

What is ImmuGuard?

#1ImmuGuard – Bovine Colostrum Immune Support
Registered 2022/36523 g sachets

ImmuGuard – Bovine Colostrum Immune Support

Bovine colostrum from the first 6 hours after calving, by Dulex Lab

EGP 115

pack of 7 sachets · current price from the product page

  • The box: bovine colostrum 1000 mg per sachet, 12 kcal, with no IgG listed
  • The box: contains dairy derivatives and may contain nuts, fish oil and soy protein
  • The page: a supplement, not a medicine, and no substitute for rehydration solution or vaccines

Heads-up: Not for cow’s milk protein allergy; pregnancy, breastfeeding and chronic conditions: ask first

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What side effects were actually recorded?

Source Who and how What was recorded
Assiut study 2016 (Saad) 160 children aged 1 to 6 with recurrent infections, 4 weeks, open study with no comparison group Mild effects in 7.5 percent: rash in 9 children, itch in 1 and diarrhoea in 2
Ain Shams study 2026 (Said) 60 children with congenital urinary-tract anomalies and recurrent infection, one month, double-blind versus placebo, 6-month follow-up No adverse events or allergy were recorded
Alexandria study (Barakat) 160 children with acute diarrhoea, one week, double-blind It measured diarrhoea, vomiting and fever, not side effects, so we cannot say it proved safety
Sangild review 2021 A review of bovine colostrum in children Allergy and intolerance appear unlikely when it is a supplement within normal nutrition, and exclusive colostrum feeding for infants is not recommended
Davison study 2020 Healthy adults, 20 to 40 g colostrum, up to 12 weeks It did not raise IGF-1 in the blood, a theoretical concern
ImmuGuard safety numbers
Sources on PubMed: Saad 2016 · Said 2026 · Davison 2020 · Sangild 2021.

These numbers come from small, short studies, and there is no long-term follow-up on ImmuGuard itself. And the dose in the growth-factor study (20 to 40 g) is far higher than the 1 g of colostrum in a sachet.

Who should ask a doctor first?

  • Cow’s milk protein allergy: ImmuGuard contains bovine colostrum and skimmed milk, and the page says it is not to be used with it.
  • Nut, fish or soy allergy: the box says it may contain traces of them.
  • A baby under 6 months: only after a doctor says so (from the page).
  • Premature babies: the only study on them was in a NICU under doctors’ supervision, and independent reviews did not confirm its results, so we do not suggest it for preterm babies without a neonatologist.
  • Pregnancy, breastfeeding and chronic conditions: the page asks you to consult a doctor.
  • A child with congenital urinary-tract anomalies: only under a kidney doctor (from the Ain Shams study).
  • Dehydration, blood in the stool or a child who is not drinking: a doctor at once, and ImmuGuard is not a substitute for rehydration solution.

Dose and how to use it

  • On the box: empty the sachet into half a cup of water, milk or juice and stir until dissolved. No age-based dose is printed on the box.
  • In the studies: one sachet a day under two years and two sachets over two years (Assiut, one month), and one sachet a day for a week in Alexandria.
  • The doses suggested on the page for infection and prevention are labelled as suggested, not from the box, and adult doses were not studied on ImmuGuard.
  • No study on time of day, and the page mentions an empty stomach half an hour before food following the studies’ description.
ImmuGuard safety caveats
Sources: the product page and box · Saad 2016 · Said 2026 · Davison 2020.

Ask a doctor or pharmacist first if

  • The child has a milk-protein allergy or a nut, fish or soy allergy.
  • The child is under 6 months or was born preterm.
  • The child or adult has a chronic condition or takes medicines regularly.
  • Pregnancy or breastfeeding.
  • A rash, itch or diarrhoea appeared after the first use.

Want to ask?

Beseha pharmacists answer on WhatsApp. Tap the “Ask a pharmacist” button and tell them the child’s age and condition before you start.

FAQ

Does ImmuGuard have side effects?

Mild effects (rash, itch and diarrhoea) were recorded in 7.5 percent of 160 children in the open Assiut study, and none were recorded in 60 children in the 2026 Ain Shams study. Both studies are small and short.

Is ImmuGuard suitable for a child with a milk allergy?

No, it contains bovine colostrum and skimmed milk, and the page says it is not to be used with cow’s milk protein allergy.

From what age can ImmuGuard be used?

The page says from 6 months, and younger only after a doctor says so. The Alexandria study covered 6 months to 2 years.

Could it raise IGF-1?

A study in healthy adults on 20 to 40 g of colostrum found no rise in IGF-1, but the dose is far above a sachet and it was in adults.

Does it replace rehydration solution or vaccines?

No, the page says it is not a substitute. With dehydration or blood in the stool, see a doctor at once.

Should I ask a doctor before giving it to my child?

We suggest so, especially if the child is under 6 months, was born preterm or has an allergy or a chronic condition.

Read next: Is bovine colostrum safe for children?, the Alexandria University trial on childhood diarrhoea and ImmuGuard and bovine colostrum: what the research shows.

The bottom line

ImmuGuard is a registered supplement, and the side effects recorded in the studies were mild and few, but the studies are small and short. It is not for cow’s milk allergy, not a substitute for rehydration solution, and you should ask the child’s doctor before use, especially for under 6 months, preterm babies and anyone with a chronic condition.

ImmuGuard at Beseha →

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