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Do Iron Supplements Cause Constipation? How to Avoid It

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Iron and constipation: how to avoid it

Reviewed by the Beseha pharmacist team · Updated 3 November 2026 · Prices taken from Beseha product pages on that day · 5-minute read

The 30-second answer

Yes, iron can cause constipation: the NHS lists constipation or diarrhoea, tummy pain, feeling sick and darker poo, and a review of 43 trials found ferrous sulfate raises digestive side effects (OR 2.32). You can lessen it by taking it with or soon after food, adding fibre, water and walking, and asking your doctor about alternate-day dosing; do not stop iron by yourself.

Why does iron cause constipation?

The NHS counts constipation as a common side effect of iron tablets, along with diarrhoea, tummy pain, heartburn, feeling sick and darker poo. A 2015 review (43 trials, 6,831 adults) found ferrous sulfate raised the risk of digestive side effects versus placebo (OR 2.32, interval 1.74 to 3.08) and versus intravenous iron (OR 3.05), and in pregnant women (7 trials) OR 3.33. Surprisingly the review found no relation between side effects and dose. Per the NHS, doses above 20 mg a day may cause constipation, nausea, vomiting and stomach pain.

Iron and constipation: research numbers
Sources: Tolkien 2015 (PubMed) and the NHS.

How to lessen it

  • With food: the NHS says take the tablet with or soon after food to reduce side effects, keep taking it even if they appear, and tell your doctor.
  • Fibre, water and movement: the NHS advises fruit, vegetables and cereals, plenty of water, and a daily walk or run; a difference may show within days or weeks.
  • Alternate days: in a trial (150 women, ferritin ≤30) the same total dose on alternate days gave the same ferritin as daily dosing (44.8 vs 43.8) and fewer digestive side effects (on iron days, 1.56 times more with daily dosing). But it was in women with low stores, not confirmed anaemia, so ask your doctor before changing the schedule.
  • Ask a pharmacist: if food changes do not help, the NHS says a pharmacist can suggest a suitable laxative.
  • No source we opened shows a particular form is gentler: not liposomal, liquid or bisglycinate; so we do not repeat “gentle on the stomach” claims from product pages.
Steps to reduce iron constipation
Sources: NHS and von Siebenthal 2023.

Iron products at Beseha

The full guide to iron types is in iron supplements in Egypt. Here are four people ask about, with the stated dose. Test first, and the dose is set with your doctor.

#1Ferrocal Forte – 20 Capsules
30 mg ironAfter food

Ferrocal Forte – 20 Capsules

Iron with vitamin C, B12, folic acid and zinc

EGP 170

EGP 8.5 per day · 20 days

  • The page: each capsule has 30 mg iron, 120 mg vitamin C and 10 mcg B12
  • The page: one capsule a day after food with enough water
  • 20 capsules = 20 days

Heads-up: The page calls it “stomach-friendly”, which we found no source for; and 30 mg is above the 20 mg the NHS says may cause constipation

Buy at Beseha →

#2Sleevar Iron – 30 Capsules
45 mg iron21 vitamins and minerals

Sleevar Iron – 30 Capsules

One capsule after the main meal

EGP 390

EGP 13.0 per day · 30 days

  • The page: 45 mg iron per capsule with B vitamins, A, C, D3, E and K1
  • The page: one capsule after the main meal, keeping tea, coffee, milk and calcium 2 hours apart
  • 30 capsules = 30 days

Heads-up: 45 mg is the adult upper limit per the page, and well above the NHS 20 mg; not for pregnancy, and do not add another iron product

Buy at Beseha →

#3Dulefer Lactoferrin 100 mg – 14 Sachets
No ironLactoferrin

Dulefer Lactoferrin 100 mg – 14 Sachets

A milk protein that binds iron, with no iron in it

EGP 200

EGP 14.3 per day · 14 days

  • The page: 100 mg lactoferrin per 5 g sachet, no iron
  • The page: prevention 1 sachet a day; iron deficiency 2 a day as your doctor advises
  • A 2017 pregnancy meta-analysis: fewer digestive side effects than ferrous sulfate

Heads-up: It contains dairy derivatives; and it does not replace anaemia treatment prescribed by your doctor

Buy at Beseha →

#4Nature's Way Liquid Iron – 480 ml
18 mg iron per 5 mlLiquid

Nature’s Way Liquid Iron – 480 ml

A berry-flavoured liquid iron

EGP 1,400

EGP 14.6 per day · 96 days

  • The page: every 5 ml has 18 mg iron (ferrous gluconate)
  • The page: 5 ml a day or as your doctor advises
  • The page: adults, teens and children over 4; 480 ml = 96 doses

Heads-up: The page says it “doesn’t cause constipation”, which we do not repeat: the NHS lists constipation for iron in general. It contains sorbitol

Buy at Beseha →

Product Iron per dose Price Per day
Ferrocal Forte – 20 Capsules 30 mg EGP 170 EGP 8.5
Sleevar Iron – 30 Capsules 45 mg EGP 390 EGP 13.0
Dulefer Lactoferrin 100 mg – 14 Sachets No iron EGP 200 EGP 14.3
Nature’s Way Liquid Iron – 480 ml 18 mg (5 ml) EGP 1,400 EGP 14.6

Ask your doctor or pharmacist first if

  • You have not had a test (blood count and ferritin) and take iron by yourself: extra iron is not helpful.
  • Constipation does not improve with food changes, or there is severe pain or blood in the stool.
  • You are pregnant: some of these products are not for pregnancy per their pages.
  • You take levothyroxine, an antibiotic or an antacid: separate them per the product page.
  • Children: an iron overdose in a young child can be fatal per the NHS, so keep it out of reach.

Want to ask?

Beseha pharmacists answer on WhatsApp. Tap the “Ask a pharmacist” button and tell them your tests and medicines.

FAQ

Does iron cause constipation?

Yes, the NHS lists constipation or diarrhoea, tummy pain, feeling sick and darker poo among the effects of iron tablets, and a review of 43 trials found more digestive side effects with ferrous sulfate (OR 2.32).

How do I avoid iron constipation?

Take the tablet with or soon after food, add fibre, water and daily walking per the NHS, and ask your doctor about alternate-day dosing.

Should I stop iron if it causes constipation?

No; the NHS advises to keep taking the tablets even with side effects and to tell the doctor, who may ask for follow-up tests.

Does liquid or liposomal iron avoid constipation?

We found no evidence in the sources we opened that any particular form is gentler, and the NHS lists constipation for iron in general.

Is lactoferrin an alternative?

A 2017 pregnancy review found fewer digestive side effects with lactoferrin than ferrous sulfate, but it contains no iron, and treatment is directed by your doctor.

When should I see a doctor about constipation?

If it does not improve with diet changes, or there is severe pain or blood in the stool; and a pharmacist can suggest a suitable laxative per the NHS.

Read next: iron supplements in Egypt and signs of nutritional deficiency.

The bottom line

Constipation is a known effect of iron. Take it with or after food, and add fibre, water and walking. Ask your doctor about alternate-day dosing, do not stop iron by yourself, and do not believe “no constipation” promises without a source.

Iron and minerals at Beseha →

Sources

This content is for information and is not a substitute for advice from a doctor or pharmacist. Prices and availability may change; the final price is on the product page.

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