Hyaluronic acid holds water and hydrates the skin, and Cleveland Clinic says it is safe with rare reactions. Apply it to damp skin after washing, then seal it with a moisturising cream. A higher strength is not required: a trial found better hydration and elasticity with a 0.1% cream. Good options: Moist-1 at EGP 250, Derma Ten at EGP 330 and Vichy Mineral 89.
With niacinamide
What does hyaluronic acid do?
- Your body already makes it: Cleveland Clinic says it is produced naturally, mostly in the eyes, joints and skin.
- It holds water: per the same source, a quarter-teaspoon holds about one and a half gallons of water.
- Key to skin moisture: a 2012 review called it the key molecule in skin moisture, and said youthful firmness and elasticity depend largely on the skin’s water content.
- Wrinkles: Cleveland Clinic says it is especially useful for reducing the appearance of wrinkles and lines, and helps wounds heal faster.

What the research shows
- The trial: in 2011, 0.1% hyaluronic acid creams were tested around the eyes of 76 women aged 30 to 60, twice a day for 60 days, against a cream without it.
- The result: every molecular weight improved hydration and elasticity, but wrinkle depth fell clearly only with the low molecular weights.
- Strength: that trial used 0.1%, so a 2% or 3% serum is not necessarily better; consistency and a moisturiser on top matter more.
- Safety: Cleveland Clinic says reactions are rare and it is safe in pregnancy and breastfeeding.
Serums with a stated strength
Moist-1 Hyaluronic Acid Serum 2% – 30 ml
The cheapest serum with a stated strength
EGP 250
EGP 8.3 per ml · 30 ml
- The pack says 2% hyaluronic acid with collagen peptides and vitamins B3 and B5
- The page says morning and evening, then a suitable moisturiser
- The pack says all skin types, for face and neck
Heads-up: The page says it suits oily skin too, but gives no detail on fragrance
Derma Ten Hydra Power Hyaluronic Acid 2% – 30 ml
2% hyaluronic acid in high and low molecular weights
EGP 330
EGP 11.0 per ml · 30 ml
- The pack says 2% hyaluronic acid for multi-depth rehydration and fine lines
- The page lists high and extra-low molecular weight HA, plus alpha arbutin, niacinamide and lactic acid
- The page says all skin types, morning and evening
Heads-up: It contains lactic acid; if your skin is sensitive, patch test first
Bionnex The Nordea Hyaluronic Acid 2% – 30 ml
2% hyaluronic acid with algae and vitamin B5
EGP 619
EGP 20.6 per ml · 30 ml
- The pack says 2% hyaluronic acid with Arctic algae and vitamin B5
- The pack says for all skin types, morning and night
- The page says it absorbs fast and layers well
Heads-up: 2% does not mean better results; the trial that found benefits used a 0.1% cream
StarVille Hyaluronic Acid Serum 3% – 30 ml
3% hyaluronic acid with vitamins E and B
EGP 290
EGP 9.7 per ml · 30 ml
- The pack says 3% hyaluronic acid with vitamin E and B vitamins
- The pack says all skin types, hypoallergenic, for face and neck
- The pack says an extra-light texture
Heads-up: The page does not mention the strength, but the pack says 3%
Other serums
Vichy Mineral 89 Booster – 50 ml
A light daily gel booster for hydration
EGP 1,2151,350
EGP 24.3 per ml · 50 ml
- The pack says H.A. + P.G.A., hydrating and plumping, for daily use
- The page says mineral-rich water with hyaluronic acid, in a light texture that layers under other products
- 50 ml, larger than the rest
Heads-up: The hyaluronic acid strength is not stated; and it is the priciest pick
Kolagra Hyaluronic Acid Serum – 30 ml
A hyaluronic acid serum rich in vitamin B5
EGP 335
EGP 11.2 per ml · 30 ml
- The pack says a hyaluronic acid serum rich in vitamin B5, soothing and repairing
- The page says it absorbs fast without a greasy feel
- 30 ml pump bottle
Heads-up: The hyaluronic acid strength is not on the pack or the page
Matriskin Hyaluronic Acid Serum – 30 ml
A light serum that layers under moisturiser and makeup
EGP 719799
EGP 24.0 per ml · 30 ml
- The page says it absorbs fast and layers under moisturiser and makeup
- The page says it suits dry, combination and normal skin
- Pump bottle
Heads-up: The strength is not stated, and the size is in the name but not visible in the photo
Comparison table
| Product | Best for | Strength | Price | Per ml |
|---|---|---|---|---|
| Moist-1 Hyaluronic Acid Serum 2% – 30 ml | Lowest price | 2% | EGP 250 | EGP 8.3 |
| StarVille Hyaluronic Acid Serum 3% – 30 ml | All skin types | 3% | EGP 290 | EGP 9.7 |
| Derma Ten Hydra Power Hyaluronic Acid 2% – 30 ml | Dehydration lines | 2% | EGP 330 | EGP 11.0 |
| Kolagra Hyaluronic Acid Serum – 30 ml | Hydrate and soothe | Not stated | EGP 335 | EGP 11.2 |
| Bionnex The Nordea Hyaluronic Acid 2% – 30 ml | All skin types | 2% | EGP 619 | EGP 20.6 |
| Matriskin Hyaluronic Acid Serum – 30 ml | Dry, combination | Not stated | EGP 719 | EGP 24.0 |
| Vichy Mineral 89 Booster – 50 ml | Daily, under makeup | Not stated | EGP 1,215 | EGP 24.3 |
How to apply it

- Damp skin: the American Academy of Dermatology says to apply moisturiser while your skin is still damp after washing or a shower.
- Seal with cream: the same source says creams and ointments add more moisture than lotions, and lists hyaluronic acid and glycerin among the ingredients to look for.
- Fragrance free: the AAD recommends “fragrance-free” products, not “unscented” ones, which may contain chemicals that mask odours.
- Water: a 5 to 10-minute shower in warm water, per the same source.
- With other products: see also niacinamide for skin and the best vitamin C serums in Egypt.
Common mistakes
- Higher strength = better: the trial that found benefits used 0.1%.
- Serum without moisturiser: the AAD advises a cream to seal in moisture.
- On bone-dry skin: apply it while your skin is still damp.
- Treating injections like serums: Cleveland Clinic says hyaluronic acid injections must be given by a trained, qualified professional, and misuse can cause severe complications.
- Harsh cleansing: choose a gentle cleanser; see the best micellar water in Egypt.
Keep in mind
- Cleveland Clinic says products that combine hyaluronic acid with other medicines or compounds may carry some risk of side effects, so tell your doctor everything you use.
- If your skin stays dry despite moisturising, the AAD says to see a dermatologist, as ongoing dryness can be linked to conditions such as eczema or psoriasis.
- Patch test any new serum on a small area first if your skin is sensitive.
Not sure which one?
Beseha pharmacists answer on WhatsApp. Tap the “Ask a pharmacist” button, tell them your skin type and what you use now, and they will help you choose.
FAQ
What does hyaluronic acid do for skin?
It holds water and hydrates the skin. Cleveland Clinic says it helps reduce the look of wrinkles and lines, and a trial found better hydration and elasticity after 60 days.
What is the best hyaluronic acid serum in Egypt?
By budget: Moist-1 at 2% is the cheapest, Derma Ten Hydra Power combines several molecular weights, and Vichy Mineral 89 is a light daily gel.
Is a higher strength better?
Not necessarily. The trial that found benefits used a 0.1% cream, and only the low molecular weights reduced wrinkle depth.
How do I use a hyaluronic acid serum?
On skin that is still damp after washing, then a moisturising cream on top. The AAD advises moisturiser on damp skin and fragrance-free products.
Is hyaluronic acid safe in pregnancy?
Cleveland Clinic says it is safe in pregnancy and breastfeeding, and reactions are rare.
Does it suit oily skin?
Most serums here say they suit all skin types, and the Moist-1 page says it suits oily skin.
Is a serum the same as hyaluronic acid injections?
No. Injections are a medical procedure for a trained professional; a serum is a topical product for hydration.
Read next: niacinamide for skin and the best vitamin C serums in Egypt.
The bottom line
Hyaluronic acid is a safe moisturising ingredient that holds water in the skin. Apply it to damp skin after washing and seal with a cream, choosing fragrance free if your skin is sensitive. A high strength is not required, and consistency matters more. If dryness continues, see a dermatologist.
Sources
- Cleveland Clinic: Hyaluronic acid
- American Academy of Dermatology: Tips to relieve dry skin
- Pavicic et al. 2011: Hyaluronic acid creams of different molecular weights for wrinkles
- Papakonstantinou et al. 2012: Hyaluronic acid, a key molecule in skin aging
This content is for information and is not a substitute for advice from a doctor or pharmacist. Prices and availability may change; the final price is on the product page.






